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Publikationen

Cardiorespiratory response to exercise after renal sympathetic denervation in patients with resistant hypertension.
Ukena C, Mahfoud F, Kindermann I, Barth C, Lenski M, Kindermann M, Brandt MC, Hoppe UC, Krum H, Esler M, Sobotka PA, Böhm M.
J Am Coll Cardiol. 2011; 58(11):1176-82.

Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: a pilot study.
Mahfoud F, Schlaich M, Kindermann I, Ukena C, Cremers B, Brandt MC, Hoppe UC, Vonend O, Rump LC, Sobotka PA, Krum H, Esler M, Böhm M.
Circulation. 2011; 123(18):1940-6.

Long-term safety and efficacy of aliskiren and valsartan combination with or without the addition of HCT in patients with hypertension.
Chrysant SG, Murray AV, Hoppe UC, Dattani D, Patel S, Ritter S, Zhang J.
Curr Med Res Opin. 2010;26(12):2841-9.

Impact of rescue-thrombolysis during cardiopulmonary resuscitation in patients with pulmonary embolism.
Er F, Nia AM, Gassanov N, Caglayan E, Erdmann E, Hoppe UC.
PLoS One. 2009; 4(12):e8323.

Impact of dihydrotestosterone on L-type calcium channels in human ventricular cardiomyocytes.
Er F, Gassanov N, Brandt MC, Madershahian N, Hoppe UC.
Endocr Res. 2009; 34(3):59-67.

Effectiveness and safety of percutaneous coronary sinus-based mitral valve repair in patients with dilated cardiomyopathy (from the AMADEUS trial).
Siminiak T, Hoppe UC, Schofer J, Haude M, Herrman JP, Vainer J, Firek L, Reuter DG, Goldberg SL, Van Bibber R.
Am J Cardiol. 2009; 104(4):565-70.

Distinct regulation of cardiac I(f) current via thyroid receptors alpha1 and beta1.
Gassanov N, Er F, Endres-Becker J, Wolny M, Schramm C, Hoppe UC.
Pflugers Arch. 2009; 458(6):1061-8.

Transgenic simulation of human heart failure-like L-type Ca2+-channels: implications for fibrosis and heart rate in mice.
Beetz N, Hein L, Meszaros J, Gilsbach R, Barreto F, Meissner M, Hoppe UC, Schwartz A, Herzig S, Matthes J.
Cardiovasc Res. 2009; 84(3):396-406.

Percutaneous mitral annuloplasty for functional mitral regurgitation: results of the CARILLON Mitral Annuloplasty Device European Union Study.
Schofer J, Siminiak T, Haude M, Herrman JP, Vainer J, Wu JC, Levy WC, Mauri L, Feldman T, Kwong RY, Kaye DM, Duffy SJ, Tübler T, Degen H, Brandt MC, Van Bibber R, Goldberg S, Reuter DG, Hoppe UC.
Circulation. 2009; 120(4):326-33.

Percutaneous mitral annuloplasty device leaves free access to cardiac veins for resynchronization therapy.
Hoppe UC
, Brandt MC, Degen H, Dodos F, Schneider T, Stoepel C, Kroener A, Haude M.
Catheter Cardiovasc Interv. 2009; 74(3):506-11.

Chronic monitoring of pulmonary artery pressure in patients with severe heart failure: multicentre experience of the monitoring Pulmonary Artery Pressure by Implantable device Responding to Ultrasonic Signal (PAPIRUS) II study.
Hoppe UC
, Vanderheden M, Sievert H, Brandt MC, Tobar R, Wijns W, Rozenman Y.
Heart. 2009; 95(13):1091-7.

Divergent regulation of cardiac KCND3 potassium channel expression by the thyroid hormone receptors alpha1 and beta1.
Gassanov N, Er F, Michels G, Zagidullin N, Brandt MC, Hoppe UC.
J Physiol. 2009; 587(Pt 6):1319-29.

Long QT syndrome-associated mutations in KCNQ1 and KCNE1 subunits disrupt normal endosomal recycling of IKs channels.
Seebohm G, Strutz-Seebohm N, Ureche ON, Henrion U, Baltaev R, Mack AF, Korniychuk G, Steinke K, Tapken D, Pfeufer A, Kääb S, Bucci C, Attali B, Merot J, Tavare JM, Hoppe UC, Sanguinetti MC, Lang F.
Circ Res. 2008; 103(12):1451-7.

Retinoid acid-induced effects on atrial and pacemaker cell differentiation and expression of cardiac ion channels.
Gassanov N, Er F, Zagidullin N, Jankowski M, Gutkowska J, Hoppe UC.
Differentiation. 2008; 76(9):971-80.

Long-term safety, tolerability and efficacy of aliskiren in combination with valsartan in patients with hypertension: a 6-month interim analysis.
Chrysant SG, Murray AV, Hoppe UC, Dattani D, Patel S, Hsu H, Zhang J.
Curr Med Res Opin. 2008; 24(4):1039-47.

Direct evidence for calcium conductance of hyperpolarization-activated cyclic nucleotide-gated channels and human native If at physiological calcium concentrations.
Michels G, Brandt MC, Zagidullin N, Khan IF, Larbig R, van Aaken S, Wippermann J, Hoppe UC.
Cardiovasc Res. 2008; 78(3):466-75.

K+ channel regulator KCR1 suppresses heart rhythm by modulating the pacemaker current If.
Michels G, Er F, Khan IF, Endres-Becker J, Brandt MC, Gassanov N, Johns DC, Hoppe UC.
PLoS One. 2008; 3(1):e1511.

Usefulness of myocardial performance index and biochemical markers for early detection of anthracycline-induced cardiotoxicity in adults.
Dodos F, Halbsguth T, Erdmann E, Hoppe UC.
Clin Res Cardiol. 2008; 97(5):318-26.

Effect of cardiac resynchronization on morbidity and mortality of diabetic patients with severe heart failure.
Hoppe UC
, Freemantle N, Cleland JG, Marijianowski M, Erdmann E.
Diabetes Care. 2007; 30(3):722-4.

Arginine vasopressin-mediated cardiac differentiation: insights into the role of its receptors and nitric oxide signaling.
Gassanov N, Jankowski M, Danalache B, Wang D, Grygorczyk R, Hoppe UC, Gutkowska J.
J Biol Chem. 2007; 282(15):11255-65.

Mechanism of Ca(v)1.2 channel modulation by the amino terminus of cardiac beta2-subunits.
Herzig S, Khan IF, Gründemann D, Matthes J, Ludwig A, Michels G, Hoppe UC, Chaudhuri D, Schwartz A, Yue DT, Hullin R.
FASEB J. 2007; 21(7):1527-38.

Enrichment of cardiac pacemaker-like cells: neuregulin-1 and cyclic AMP increase I(f)-current density and connexin 40 mRNA levels in fetal cardiomyocytes.
Ruhparwar A, Er F, Martin U, Radke K, Gruh I, Niehaus M, Karck M, Haverich A, Hoppe UC.
Med Biol Eng Comput. 2007; 45(2):221-7.

Impact of testosterone on cardiac L-type calcium channels and Ca2+ sparks: acute actions antagonize chronic effects.
Er F, Michels G, Brandt MC, Khan I, Haase H, Eicks M, Lindner M, Hoppe UC.
Cell Calcium. 2007 May;41(5):467-77.

Long-term and immediate effect of testosterone on single T-type calcium channel in neonatal rat cardiomyocytes.
Michels G, Er F, Eicks M, Herzig S, Hoppe UC.
Endocrinology. 2006; 147(11):5160-9.

Effect of cardiac resynchronization on the incidence of atrial fibrillation in patients with severe heart failure.
Hoppe UC
, Casares JM, Eiskjaer H, Hagemann A, Cleland JG, Freemantle N, Erdmann E.
Circulation. 2006; 114(1):18-25.

Correlation between serial measurements of N-terminal pro brain natriuretic peptide and ambulatory cardiac filling pressures in outpatients with chronic heart failure.
Braunschweig F, Fahrleitner-Pammer A, Mangiavacchi M, Ghio S, Fotuhi P, Hoppe UC, Linde C.
Eur J Heart Fail. 2006; 8(8):797-803.

Angiotensin II-induced changes of calcium sparks and ionic currents in human atrial myocytes: potential role for early remodeling in atrial fibrillation.
Gassanov N, Brandt MC, Michels G, Lindner M, Er F, Hoppe UC.
Cell Calcium. 2006 Feb;39(2):175-86.

Single-channel properties support a potential contribution of hyperpolarization-activated cyclic nucleotide-gated channels and If to cardiac arrhythmias.
Michels G, Er F, Khan I, Südkamp M, Herzig S, Hoppe UC.
Circulation. 2005; 111(4):399-404.

Testosterone induces cytoprotection by activating ATP-sensitive K+ channels in the cardiac mitochondrial inner membrane.
Er F, Michels G, Gassanov N, Rivero F, Hoppe UC.
Circulation. 2004; 110(19):3100-7.

Endothelin induces differentiation of ANP-EGFP expressing embryonic stem cells towards a pacemaker phenotype.
Gassanov N, Er F, Zagidullin N, Hoppe UC.
FASEB J. 2004; 18(14):1710-2.

Andersen mutations of KCNJ2 suppress the native inward rectifier current IK1 in a dominant-negative fashion.
Lange PS, Er F, Gassanov N, Hoppe UC.
Cardiovasc Res. 2003; 59(2):321-7.

Dominant-negative suppression of HCN channels markedly reduces the native pacemaker current I(f) and undermines spontaneous beating of neonatal cardiomyocytes.
Er F, Larbig R, Ludwig A, Biel M, Hofmann F, Beuckelmann DJ, Hoppe UC.
Circulation. 2003; 107(3):485-9.

Functional consequences of the arrhythmogenic G306R KvLQT1 K+ channel mutant probed by viral gene transfer in cardiomyocytes.
Li RA, Miake J, Hoppe UC, Johns DC, Marbán E, Nuss HB.
J Physiol. 2001; 533(Pt 1):127-33.

Distinct gene-specific mechanisms of arrhythmia revealed by cardiac gene transfer of two long QT disease genes, HERG and KCNE1.
Hoppe UC
, Marbán E, Johns DC.
Proc Natl Acad Sci U S A. 2001; 98(9):5335-40.

Adenovirus-mediated inducible gene expression in vivo by a hybrid ecdysone receptor.
Hoppe UC
, Marbán E, Johns DC.
Mol Ther. 2000; 1(2):159-64.

Infarct related artery patency: relation to serial electropharmacological studies and outcome in patients with previous myocardial infarction and ventricular tachyarrhythmias.
Hoppe UC
, Haverkamp W, Breithardt G, Borggrefe M.
Pacing Clin Electrophysiol. 2000; 23(5):854-62.

Molecular dissection of cardiac repolarization by in vivo Kv4.3 gene transfer.
Hoppe UC
, Marbán E, Johns DC.
J Clin Invest. 2000; 105(8):1077-84.

Manipulation of cellular excitability by cell fusion: effects of rapid introduction of transient outward K+ current on the guinea pig action potential.
Hoppe UC
, Johns DC, Marbán E, O'Rourke B.
Circ Res. 1999; 84(8):964-72.

Modulation of the hyperpolarization-activated inward current (If) by antiarrhythmic agents in isolated human atrial myocytes.
Hoppe UC
, Beuckelmann DJ.
Naunyn Schmiedebergs Arch Pharmacol. 1998; 358(6):635-40.

Characterization of the hyperpolarization-activated inward current in isolated human atrial myocytes.
Hoppe UC
, Beuckelmann DJ.
Cardiovasc Res. 1998; 38(3):788-801.

Hyperpolarization-activated inward current in ventricular myocytes from normal and failing human hearts.
Hoppe UC
, Jansen E, Südkamp M, Beuckelmann DJ.
Circulation. 1998; 97(1):55-65.

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